Living Organisms
Cayman Chemical Clodronate (sodium salt hydrate), Purity: ≥95%, CAS: 88416-50-6, 10 mg
A non-nitrogenous bisphosphonate that inhibits hydroxyapatite crystal growth (IC50 = 1.34 µM) and bone resorption; is cytotoxic to both osteoclasts and macrophages and has been used in biological research to selectively induce apoptosis of macrophage-like cells and cancer cells
Cayman Chemical Harmalol (hydrochloride hydrate), Purity: ≥98%, CAS: 6028-00-8, 100 mg
A β-carboline alkaloid and an active metabolite of harmaline; an inhibitor of DYRK1A (IC50 = 0.63 µM); an inhibitor of MAO-A (IC50 = 0.66 µM); selective for DYRK1A over Cdk1, Cdk5, CK1α1, Clk4, DYRK2, Pim-1, and GSK3β but also inhibits DYRK1B and Clk1 at 10 µM; inhibits proliferation of H4 human glioblastoma cells (IC50s = 23.7 µM); reduces TCDD-induced increases in CYP1A1 levels in HepG2 cells and prevents TCDD-induced activation of AhR in guinea pig hepatic cytosolic extracts; reduces glutamate-induced cytotoxicity, cytochrome c release, caspase-3 activation, and ROS production in PC12 cells at 25 µM
Cayman Chemical Cefepime (hydrochloride hydrate), Purity: ≥90%, CAS: 123171-59-5, 5 g
A cephalosporin antibiotic; inhibits the growth of some clinical isolates of Corynebacterium, Streptococcus, and Staphylococcus (MIC90s = 0.03-8 μg/ml); inhibits the growth of some Citrobacter, Enterobacter, Klebsiella, Salmonella, Serratia, Shigella, and enteric bacilli species in addition to P. mirabilis and E. coli clinical isolates (MIC90s = ≤0.12-2 μg/ml); inhibits the growth of pneumococci strains (MICs = 0.5-2 mg/l) in vitro and in vivo in a mouse model of peritonitis (ED50s = 0.6-1.14 mg/kg)
AdipoGen ANTS
Chemical. CAS 5398-34-5. Formula C10H7NNa2O9S3. Molecular Weight 427.34. ANTS is a highly negatively charged dye with an amino group that can be coupled to an aldehyde or ketone group to form an unstable Schiff base. The Schiff base is usually chemically reduced by sodium borohydride NaBH4 or sodium cyanoborohydride NaBCNH3 to form a stable linkage. This labeling technique has been widely used for the labeling and subsequent sequencing of oligosaccharides and glycoproteins. The negative charges of the dye facilitate the electrophoretic separation of the degradation products of carbohydrate polymers. The polyanionic dye ANTS is used together with the fluorescent cationic quencher DPX for membrane fusion studies or permeability assays. The mixture of ANTS-DPX is minimally fluorescent initially, but becomes increasingly more fluorescent upon dilution i.e. membrane fusion or leakage. ANTS also is used as a neuronal tracer.
Cayman Chemical Harmalol (hydrochloride hydrate), Purity: ≥98%, CAS: 6028-00-8, 500 mg
A β-carboline alkaloid and an active metabolite of harmaline; an inhibitor of DYRK1A (IC50 = 0.63 µM); an inhibitor of MAO-A (IC50 = 0.66 µM); selective for DYRK1A over Cdk1, Cdk5, CK1α1, Clk4, DYRK2, Pim-1, and GSK3β but also inhibits DYRK1B and Clk1 at 10 µM; inhibits proliferation of H4 human glioblastoma cells (IC50s = 23.7 µM); reduces TCDD-induced increases in CYP1A1 levels in HepG2 cells and prevents TCDD-induced activation of AhR in guinea pig hepatic cytosolic extracts; reduces glutamate-induced cytotoxicity, cytochrome c release, caspase-3 activation, and ROS production in PC12 cells at 25 µM
Percival Scientific Arabidopsis Growth Chamber, AR41L2H11, 37.2 cu. ft., SciWhite with red LEDs, 2 tiers, 7-44° C ±0.5°, IntellusUltra controller, touchscreen, advanced additive ultrasonic humidifier
The AR41L2H11 growth chamber is designed for growth of Arabidopsis thaliana and low light plant growth applications. SciWhite with red LEDs are dimmable from 10-100% output with up to 405 µmoles/m2/s irradiance @ 6". Ultrasonic humidifier and advanced humidity sensor provide additive humidity. Interior / exterior of smooth white galvanized steel with foamed-in-place non-CFC insulation and a stainless-steel floor for corrosion resistance. Adjustable air diffuser for temperature uniformity. Two white epoxy coated steel wire shelves adjustable in ½” increments. Self-contained air-cooled condensing unit with hot gas bypass system for continuous compressor operation extends life, ensuring precise temperature control by alternately cycling refrigerant and hot gas to coil; this also prolongs life of compressor, and eliminates risk of ice build up in coil. Top mounted refrigeration system allows easy access for maintenance and cleaning. Contact sales@percival-scientific.com for more options.